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SHM simulator
Code 2025

Somatic Hypermutation (SHM) Simulator Prototype

A stochastic model of B-cell antibody maturation built in pure Python. Implements a full IUPAC degenerate motif matching engine to identify AID hotspot sequences (RGYW, WRC, GNW), scales per position mutation rates by literature derived enrichment weights and immune cell state, and outputs annotated mutation logs with a hotspot pressure visualization.

Moasser Lab presentation slide
Presentation 2021

HER2/HER3 Signaling & Drug Targeting — Moasser Lab, UCSF

CV review for 2nd interview at CZ Biohub. Covers heregulin stimulation experiments across HER3 KO cell lines to investigate whether HER2 self-phosphorylation drives downstream AKT and MAPK signaling. This challenges the idea of drugs targeting the extracellular domain.

MelanoBio ethical assessment slide
Presentation 2026

Ethical Assessment of MelanoBio — UMich: SIADS 503

Ethical case study analyzing MelanoBio, a hypothetical POC focused melanoma diagnostic AI, tracing bias accumulation from research literature through neural network training to clinical deployment. Recommends outcome based governance over pre-deployment filtering alone.

CRISPR journal club presentation slide
Presentation 2024

Journal Club: Genome Wide CRISPR Screen for pre-mRNA Cleavage & Polyadenylation Factors

Journal club presentation reviewing Ni et al.'s dual fluorescence readthrough reporter system, which uses a genome wide CRISPR Cas9 screen across 18,053 genes to identify both known and novel cleavage and polyadenylation factors in human pre-mRNA processing.

Seanome JC slide
Presentation 2024

Protein learning models meet reduced amino acid alphabets

Can simplifying the alphabet proteins are written in actually improve how well a model understands them? This journal club presentation for Seanome unpacks how reduced amino acid alphabets interact with protein language models like ESMFold

SynBioHubVis slide
Visualization 2025

Growth of SynBioHub Parts by Type (2002–2016)

Interactive timeseries of synthetic biology part submissions across the SynBioHub.org registry. Queried via SPARQL, cleaned with pandas, rendered in Altair. Hover, click, drag.

SHM simulator
Code 2026

Pre-Covid Analysis of Zoonotic Outbreaks and Global Production

Explore whether country level agricultural and livestock production patterns are associated with the occurrence of zoonotic disease outbreaks. By combining production statistics with case records, this analysis explores the data to uncover any patterns that may aid epidimeological characterizations of zoonotic outbreaks, before Covid 19 changed everything.